3-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-4-methoxy-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-one → 4'-methoxy-1'{[5-(trifluoromethyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

HRID 1568603Notes

Reaction equation

HRID 1568603 reaction equation
[CH:35]1([CH2:36][CH2:37][N:38]2[c:39]3[c:40]([cH:41][cH:42][cH:43][cH:44]3)[C:45]([c:46]3[c:47]([OH:48])[cH:49][c:50]4[c:54]([cH:55]3)[O:53][CH2:52][O:51]4)([CH2:56][OH:57])[C:58]2=[O:59])[CH2:60][CH2:61]1.[OH:1][c:2]1[c:3]([C:11]2([CH2:33][OH:34])[C:12](=[O:32])[N:13]([CH2:22][c:23]3[o:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH3:21])[c:19]32)[cH:4][c:5]2[c:6]([cH:10]1)[O:7][CH2:8][O:9]2>>[O:1]1[c:2]2[c:3]([cH:4][c:5]3[c:6]([cH:10]2)[O:7][CH2:8][O:9]3)[C:11]2([C:12](=[O:32])[N:13]([CH2:22][c:23]3[o:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH3:21])[c:19]32)[CH2:33]1

Participants

3

Reactant 2

HCID 588725433-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-4-methoxy-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-oneHCID 666425671-(2-cyclopropylethyl)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one

Product 1

HCID 592633974'-methoxy-1'{[5-(trifluoromethyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-492021928bed42f59ef5516db55c3001
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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