Toluene → 2-[5-(4-tert-butoxycarbonyl-piperazin-1-yl)-pyridin-2-ylamino]-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Reaction equation
[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31](=[O:32])[N:33]1[CH2:34][CH2:35][N:36]([c:39]2[cH:40][n:41][c:42]([NH2:45])[cH:43][cH:44]2)[CH2:37][CH2:38]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:25])[c:8]2[c:9]([n:10][c:11]([S:14]([CH3:15])=[O:16])[n:12][cH:13]2)[n:17]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24]2)[c:18]1=[O:19].[CH3:46][CH2:47][O:48][CH2:49][CH3:50].[CH3:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:25])[c:8]2[c:9]([n:10][c:11]([NH:45][c:42]3[n:41][cH:40][c:39]([N:36]4[CH2:35][CH2:34][N:33]([C:31]([O:30][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:32])[CH2:38][CH2:37]4)[cH:44][cH:43]3)[n:12][cH:13]2)[n:17]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24]2)[c:18]1=[O:19]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-07b915d1f9204317911153ac3bdf5b32
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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