4-Methyl-1-piperazinecarbonyl chloride → 3-Fluoro-N-((1-(4-methylpiperazine-1-carbonyl)-4-phenylpiperidin-4-yl)methyl)-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)picolinamide
Reaction equation
[CH3:38][N:39]1[CH2:40][CH2:41][N:42]([C:45](=[O:46])[Cl:47])[CH2:43][CH2:44]1.[F:1][c:2]1[c:3]([C:22](=[O:23])[NH:24][CH2:25][C:26]2([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1>>[F:1][c:2]1[c:3]([C:22](=[O:23])[NH:24][CH2:25][C:26]2([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[CH2:27][CH2:28][N:29]([C:45]([N:42]3[CH2:41][CH2:40][N:39]([CH3:38])[CH2:44][CH2:43]3)=[O:46])[CH2:30][CH2:31]2)[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7f5078d5937147879e8eba00c60fe3f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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