2-Aminocyclohexanol → 5-bromo-N-(2-hydroxycyclohexyl)-6-(pyridin-2-ylmethoxy)-2-(trifluoromethyl)pyridine-3-carboxamide
Reaction equation
[Br:1][c:2]1[c:3]([O:15][CH2:16][c:17]2[n:18][cH:19][cH:20][cH:21][cH:22]2)[n:4][c:5]([C:11]([F:12])([F:13])[F:14])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[NH2:23][CH:24]1[CH:25]([OH:30])[CH2:26][CH2:27][CH2:28][CH2:29]1>>[Br:1][c:2]1[c:3]([O:15][CH2:16][c:17]2[n:18][cH:19][cH:20][cH:21][cH:22]2)[n:4][c:5]([C:11]([F:12])([F:13])[F:14])[c:6]([C:7](=[O:9])[NH:23][CH:24]2[CH:25]([OH:30])[CH2:26][CH2:27][CH2:28][CH2:29]2)[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-e5bb0c3cbcc64045830770c475722c27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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