3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → {4-[(3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(2-methoxy-5-pyridin-4-yl-benzyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[c:17]([O:28][CH3:29])[cH:18][cH:19][c:20](-[c:22]3[cH:23][cH:24][n:25][cH:26][cH:27]3)[cH:21]2)[CH2:12][CH2:13]1)=[O:30].[Cl:31][c:32]1[c:33]2[c:34]([s:35][c:36]1[C:37](=[O:38])[Cl:39])[c:40]([F:45])[cH:41][cH:42][c:43]2[F:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[c:17]([O:28][CH3:29])[cH:18][cH:19][c:20](-[c:22]3[cH:23][cH:24][n:25][cH:26][cH:27]3)[cH:21]2)[C:37]([c:36]2[c:32]([Cl:31])[c:33]3[c:34]([s:35]2)[c:40]([F:45])[cH:41][cH:42][c:43]3[F:44])=[O:38])[CH2:12][CH2:13]1)=[O:30]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b5550f6ef1804b1c89bf30056fdf7f6f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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