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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1569053Generated: November 4, 2026

Tetrahydrofuran → tert-Butyl 2-chloro-6-(2,2,2-trifluoro-1-hydroxyethyl)isonicotinate

https://huagongshe.com/reaction/1569053

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
Reactanttert-Butyl 2-chloro-6-formylisonicotinateHCID 86657032—
Producttert-Butyl 2-chloro-6-(2,2,2-trifluoro-1-hydroxyethyl)isonicotinateHCID 86657033—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-5e17f308cf74432ca2009c23e1ea2010
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)