2-Amino-5-[4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → tert-Butyl 4-[[6-({3-(aminocarbonyl)-5-[4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)pyridin-2-yl](hydroxy)methyl]piperidine-1-carboxylate
Reaction equation
[Br:20][c:21]1[cH:22][cH:23][cH:24][c:25]([CH:27]([CH:28]2[CH2:29][CH2:30][N:31]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:32][CH2:33]2)[OH:41])[n:26]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:21]1[cH:22][cH:23][cH:24][c:25]([CH:27]([CH:28]2[CH2:29][CH2:30][N:31]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:32][CH2:33]2)[OH:41])[n:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-99603b8f048f4e21a4bcb82ef0cbcddc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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