Dichloromethane → 4-[(3-Methyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

HRID 156934Notes

Reaction equation

HRID 156934 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:15][c:16]1[c:17]([CH2:22][NH2:23])[n:18][cH:19][cH:20][cH:21]1.[Cl:24][CH2:25][Cl:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:23][CH2:22][c:17]2[c:16]([CH3:15])[cH:21][cH:20][cH:19][n:18]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 1514370(3-Methylpyridin-2-yl)methanamine

Product 1

HCID 672721764-[(3-Methyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-28ed51e32fa64beba0c403de8d2e12b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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