Acetone → N-benzyl-4-methyl-2-(2-oxopyrrolidin-1-yl)thiazole-5-carboxamide
Reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:23])[n:13][c:14]([NH:16][C:17]([CH2:18][CH2:19][CH2:20][Br:21])=[O:22])[s:15]1.[CH3:30][C:31](=[O:32])[CH3:33].[K+:28].[K+:29].[OH2:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:23])[n:13][c:14]([N:16]2[C:17](=[O:22])[CH2:18][CH2:19][CH2:20]2)[s:15]1Participants
6
Sources & evidence
- ORD record
- ord-e9f84f618465475680eb025168cfb82c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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