N,N,N',N'-Tetramethylethylenediamine → 7-(1-Benzyl-4-hydroxy-4-piperidinyl)-2,3-dihydro-2,2-dimethylbenzofuran
Reaction equation
[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[N:32]1[CH2:33][CH2:34][C:35](=[O:38])[CH2:36][CH2:37]1.[CH3:12][N:13]([CH3:14])[CH2:15][CH2:16][N:17]([CH3:18])[CH3:19].[CH3:1][C:2]1([CH3:11])[O:3][c:4]2[c:5]([cH:7][cH:8][cH:9][cH:10]2)[CH2:6]1.[CH3:20][CH2:21][CH2:22][CH2:23][Li:24].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45].[CH3:46][CH2:47][CH2:48][CH2:49][CH2:50][CH3:51]>>[CH3:1][C:2]1([CH3:11])[O:3][c:4]2[c:5]([cH:7][cH:8][cH:9][c:10]2[C:35]2([OH:38])[CH2:34][CH2:33][N:32]([CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[CH2:37][CH2:36]2)[CH2:6]1Participants
7
Sources & evidence
- ORD record
- ord-32fd569ae308461b87ef225152413f5d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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