Ethanol → N-(3-(5-amino-1-tosyl-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-4-ethylcyclopentyl)cyclopropanesulfonamide

HRID 1569685Notes

Reaction equation

HRID 1569685 reaction equation
[CH2:1]([CH3:2])[CH:3]1[CH2:4][CH:5]([NH:31][S:32](=[O:33])(=[O:34])[CH:35]2[CH2:36][CH2:37]2)[CH2:6][CH:7]1[NH:8][c:9]1[c:10]2[c:11]([n:12][cH:13][c:14]1[N+:15]([O-:16])=[O:17])[n:18]([S:21](=[O:22])(=[O:23])[c:24]1[cH:25][cH:26][c:27]([CH3:28])[cH:29][cH:30]1)[cH:19][cH:20]2.[CH3:43][CH2:44][OH:45].[OH2:38].[OH2:39].[Sn:40]([Cl:41])[Cl:42]>>[CH2:1]([CH3:2])[CH:3]1[CH2:4][CH:5]([NH:31][S:32](=[O:33])(=[O:34])[CH:35]2[CH2:36][CH2:37]2)[CH2:6][CH:7]1[NH:8][c:9]1[c:10]2[c:11]([n:12][cH:13][c:14]1[NH2:15])[n:18]([S:21](=[O:22])(=[O:23])[c:24]1[cH:25][cH:26][c:27]([CH3:28])[cH:29][cH:30]1)[cH:19][cH:20]2

Participants

5

Reactant 4

HCID 702EthanolHCID 962Water2×HCID 24479Stannous ChlorideHCID 77394394N-[3-ethyl-4-[[1-(4-methylphenyl)sulfonyl-5-nitropyrrolo[2,3-b]pyridin-4-yl]amino]cyclopentyl]cyclopropanesulfonamide

Product 1

HCID 67997957N-(3-(5-amino-1-tosyl-1H-pyrrolo[2,3-b]pyridin-4-ylamino)-4-ethylcyclopentyl)cyclopropanesulfonamide

Sources & evidence

ORD record
ord-db93428488a14a1ea47242aefdba0f41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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