Bicarbonate Ion → methyl 3-cyclohexyl-2-{3-nitro-2-[2-(tetrahydropyran-2-yloxy)ethoxy]phenyl}-1H-indole-6-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([O:4][CH2:5][CH2:6][O:7][CH:8]2[O:9][CH2:10][CH2:11][CH2:12][CH2:13]2)[c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]1.[C:21](=[O:22])([O-:23])[OH:24].[CH3:54][O:55][CH2:56][CH2:57][O:58][CH3:59].[CH:26]1([c:32]2[c:33]([B:45]3[O:46][C:47]([CH3:48])([CH3:49])[C:50]([CH3:51])([CH3:52])[O:53]3)[nH:34][c:35]3[cH:36][c:37]([C:41](=[O:42])[O:43][CH3:44])[cH:38][cH:39][c:40]23)[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]1.[Na+:25].[OH2:60].[cH:61]1[cH:62][cH:63][c:64]([P:65]([Pd:66]([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[P:105]([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)([c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)([c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[c:130]2[cH:131][cH:132][cH:133][cH:134][cH:135]2)[cH:136][cH:137]1>>[c:2]1(-[c:33]2[c:32]([CH:26]3[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]3)[c:40]3[c:35]([nH:34]2)[cH:36][c:37]([C:41](=[O:42])[O:43][CH3:44])[cH:38][cH:39]3)[c:3]([O:4][CH2:5][CH2:6][O:7][CH:8]2[O:9][CH2:10][CH2:11][CH2:12][CH2:13]2)[c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8e4f9c330e124081be1b01e633e75309
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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