2,4-Dichloro-5-fluoropyrimidine → 2-chloro-5-fluoro-N4-(4-methyl-3-trifluoromethylphenyl)-4-pyrimidineamine

HRID 1569902Notes

Reaction equation

HRID 1569902 reaction equation
[CH3:10][c:11]1[c:12]([C:18]([F:19])([F:20])[F:21])[cH:13][c:14]([NH2:15])[cH:16][cH:17]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:15][c:14]2[cH:13][c:12]([C:18]([F:19])([F:20])[F:21])[c:11]([CH3:10])[cH:17][cH:16]2)[n:7]1

Participants

3

Reactant 2

HCID 2507052,4-Dichloro-5-fluoropyrimidineHCID 27377154-Methyl-3-(trifluoromethyl)aniline

Product 1

HCID 220605602-chloro-5-fluoro-N4-(4-methyl-3-trifluoromethylphenyl)-4-pyrimidineamine

Sources & evidence

ORD record
ord-83cca5c8822a482cb0d92db3bf6c2c5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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