Imidazole → 6-Bromo-2-(tert-butyldimethylsilyloxy)-N-methyl-1-naphthamide

HRID 1569906Notes

Reaction equation

HRID 1569906 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([OH:16])[c:8]([C:12](=[O:13])[NH:14][CH3:15])[c:9]2[cH:10][cH:11]1.[C:17]([CH3:18])([CH3:19])([CH3:20])[Si:21]([CH3:22])([CH3:23])[Cl:24].[CH3:30][C:31]([O:32][I:33]1([O:43][C:44]([CH3:45])=[O:46])([O:47][C:48]([CH3:49])=[O:50])[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[C:40](=[O:41])[O:42]1)=[O:51].[nH:25]1[cH:26][cH:27][n:28][cH:29]1>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([O:16][Si:21]([C:17]([CH3:18])([CH3:19])[CH3:20])([CH3:22])[CH3:23])[c:8]([C:12](=[O:13])[NH:14][CH3:15])[c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 795ImidazoleHCID 28928tert-Butyldimethylsilyl chlorideHCID 159087TriacetoxyperiodinaneHCID 187690866-Bromo-2-hydroxy-N-methyl-1-naphthamide

Product 1

HCID 187691556-Bromo-2-(tert-butyldimethylsilyloxy)-N-methyl-1-naphthamide

Sources & evidence

ORD record
ord-fc88c266a6344a62b212092f54a732f8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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