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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1570249Generated: November 2, 2026

Dimethylformamide → (+/-)-3-[2-(4-Hydroxy-piperidin-1-yl)-thiazol-4-yl]-3-[4-(7-methoxy-quinolin-8-yl)-[1,4]diazepan-1-yl]-1-(4-methyl-piperazin-1-yl)-propan-1-one

https://huagongshe.com/reaction/1570249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant1-MethylpiperazineHCID 53167—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant(+/-)-3-[2-(4-Hydroxy-piperidin-1-yl)-thiazol-4-yl]-3-[4-(7-methoxy-quinolin-8-yl)-[1,4]diazepan-1-yl]-propionic acidHCID 59366189—
Product(+/-)-3-[2-(4-Hydroxy-piperidin-1-yl)-thiazol-4-yl]-3-[4-(7-methoxy-quinolin-8-yl)-[1,4]diazepan-1-yl]-1-(4-methyl-piperazin-1-yl)-propan-1-oneHCID 59366181—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-2d6f19c839304ae4ad9c435e0e32f7e0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)