HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157031Generated: October 25, 2026
1,4-Dioxane → 4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-6-(2-hydroxy-ethylamino)-2-[(pyridin-3-ylmethyl)-amino]-pyrimidine-5-carbonitrile
https://huagongshe.com/reaction/157031
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(4-Fluorophenyl)piperidine | HCID 2759136 | — |
| Reactant | 4-Chloro-6-(2-hydroxy-ethylamino)-2-[(pyridin-3-ylmethyl)-amino]-pyrimidine-5-carbonitrile | HCID 18753216 | — |
| Product | 4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-6-(2-hydroxy-ethylamino)-2-[(pyridin-3-ylmethyl)-amino]-pyrimidine-5-carbonitrile | HCID 18753291 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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| ORD ID | ord-a61a31d41dcc4d23ad984422cb0951bd |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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