Acetate → tert-butyl 2-[5-(5-cyanopyrazin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][N:13]([CH:15]3[CH2:16][CH2:17][c:18]4[cH:19][c:20]([Br:24])[cH:21][cH:22][c:23]43)[CH2:14]2)[CH2:25][CH2:26]1.[CH3:28][C:29](=[O:30])[O-:31].[Cl:32][c:33]1[n:34][cH:35][c:36]([C:39]#[N:40])[n:37][cH:38]1.[K+:27].[K+:41].[K+:42].[O-:43][C:44]([O-:45])=[O:46].[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][N:13]([CH:15]3[CH2:16][CH2:17][c:18]4[cH:19][c:20](-[c:33]5[n:34][cH:35][c:36]([C:39]#[N:40])[n:37][cH:38]5)[cH:21][cH:22][c:23]43)[CH2:14]2)[CH2:25][CH2:26]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-48b98015dcac4b82b6036952a7a06e6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…