3-tert-Butyl-5-isocyanato-1-phenyl-1H-pyrazole → 1-(4-(2-amino-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)urea

HRID 157063Notes

Reaction equation

HRID 157063 reaction equation
[C:25]([CH3:26])([CH3:27])([CH3:28])[c:29]1[n:30][n:31](-[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:32]([N:34]=[C:35]=[O:36])[cH:33]1.[NH2:1][c:2]1[n:3][c:4]2[c:5]([nH:6][c:7]1=[O:8])[n:9][cH:10][cH:11][c:12]2[O:13][c:14]1[cH:15][cH:16][c:17]([NH2:24])[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]12>>[NH2:1][c:2]1[n:3][c:4]2[c:5]([nH:6][c:7]1=[O:8])[n:9][cH:10][cH:11][c:12]2[O:13][c:14]1[cH:15][cH:16][c:17]([NH:24][C:35]([NH:34][c:32]2[n:31](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[n:30][c:29]([C:25]([CH3:26])([CH3:27])[CH3:28])[cH:33]2)=[O:36])[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]12

Participants

3

Reactant 2

HCID 110967603-tert-Butyl-5-isocyanato-1-phenyl-1H-pyrazoleHCID 469010952-amino-8-(4-aminonaphthalen-1-yloxy)pyrido[2,3-b]pyrazin-3(4H)-one

Product 1

HCID 441323751-(4-(2-amino-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)urea

Sources & evidence

ORD record
ord-d7f3d001eb5d41abaf77852c9e70afaf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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