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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1570631Generated: November 4, 2026

Dimethyl Sulfoxide → 2-Amino-6-(4-chloro-benzylamino)-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/1570631

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantEthanolamineHCID 700—
ReactantWaterHCID 962—
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-ChlorobenzylamineHCID 66036—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-aminochloro-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamideHCID 23130498—
Product2-Amino-6-(4-chloro-benzylamino)-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamideHCID 23130810—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-e974c5e16c2b4e08af93e945550aad85
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)