1,4-Dioxane → 2-Amino-4-difluoromethyl-5-(2-isopropyl-2H-pyrazol-3-yl)-benzoic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([F:12])[F:13])[c:8]([I:10])[cH:9]1)=[O:15].[CH:16]([CH3:17])([CH3:18])[n:19]1[n:20][cH:21][cH:22][c:23]1[Sn:24]([CH2:25][CH2:26][CH2:27][CH3:28])([CH2:29][CH2:30][CH2:31][CH3:32])[CH2:33][CH2:34][CH2:35][CH3:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([F:12])[F:13])[c:8](-[c:23]2[n:19]([CH:16]([CH3:17])[CH3:18])[n:20][cH:21][cH:22]2)[cH:9]1)=[O:15]Participants
4
Sources & evidence
- ORD record
- ord-f15fe712bfa24ffd9f67662dbae04cc7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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