4-amino-N-(6-amino-1-hydroxyhexan-2-yl)-3-chloro-N-(2-methylpropyl)benzenesulfonamide → methyl N-[1-[[5-[(4-amino-3-chlorophenyl)sulfonyl-(2-methylpropyl)amino]-6-hydroxyhexyl]amino]-3-[2-(3-fluorophenyl)phenyl]-1-oxopropan-2-yl]carbamate
Reaction equation
[F:25][c:26]1[cH:27][c:28](-[c:32]2[c:33]([CH2:38][CH:39]([C:40](=[O:41])[OH:42])[NH:43][C:44](=[O:45])[O:46][CH3:47])[cH:34][cH:35][cH:36][cH:37]2)[cH:29][cH:30][cH:31]1.[NH2:1][c:2]1[c:3]([Cl:24])[cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH2:12][CH:13]([CH3:14])[CH3:15])[CH:16]([CH2:17][CH2:18][CH2:19][CH2:20][NH2:21])[CH2:22][OH:23])[cH:6][cH:7]1>>[NH2:1][c:2]1[c:3]([Cl:24])[cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH2:12][CH:13]([CH3:14])[CH3:15])[CH:16]([CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:40]([CH:39]([CH2:38][c:33]2[c:32](-[c:28]3[cH:27][c:26]([F:25])[cH:31][cH:30][cH:29]3)[cH:37][cH:36][cH:35][cH:34]2)[NH:43][C:44](=[O:45])[O:46][CH3:47])=[O:41])[CH2:22][OH:23])[cH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-135222edd9014b708925535ad5e38c53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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