1,1-Dichloroethane → 3-(2,8-Bis(trifluoromethyl)-4-quinolinyl)-3-azetidinol

HRID 1570797Notes

Reaction equation

HRID 1570797 reaction equation
[Cl:37][C:38]([O:39][CH:40]([Cl:41])[CH3:42])=[O:43].[Cl:44][CH:45]([Cl:46])[CH3:47].[c:1]1([CH:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:31]2)[N:8]2[CH2:9][C:10]([OH:12])([c:13]3[cH:14][c:15]([C:27]([F:28])([F:29])[F:30])[n:16][c:17]4[c:18]([C:23]([F:24])([F:25])[F:26])[cH:19][cH:20][cH:21][c:22]34)[CH2:11]2)[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[NH:8]1[CH2:9][C:10]([OH:12])([c:13]2[cH:14][c:15]([C:27]([F:28])([F:29])[F:30])[n:16][c:17]3[c:18]([C:23]([F:24])([F:25])[F:26])[cH:19][cH:20][cH:21][c:22]23)[CH2:11]1

Participants

4

Reactant 3

HCID 63651,1-DichloroethaneHCID 5213051-Chloroethyl chloroformateHCID 543985001-Diphenylmethyl-3-(2,8-bis(trifluoromethyl)-4-quinolinyl)-3-azetidinol

Product 1

HCID 213547383-(2,8-Bis(trifluoromethyl)-4-quinolinyl)-3-azetidinol

Sources & evidence

ORD record
ord-7d9b93247ea34d3cbfd273cec9b466b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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