Dichloromethane → 4-(8-Methoxy-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-pyridine-2-carbonitrile

HRID 1570817Notizen

Reaktionsgleichung

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:20][C:21]([CH2:22][C:23](=[O:5])[c:25]2[cH:26][c:27]([C:31]#[N:32])[n:28][cH:29][cH:30]2)=[O:33])[cH:10][c:11]([C:16]([F:17])([F:18])[F:19])[c:12]([O:14][CH3:15])[cH:13]1)([CH3:6])([CH3:24])[CH3:34].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[N:7]1=[C:23]([c:25]2[cH:26][c:27]([C:31]#[N:32])[n:28][cH:29][cH:30]2)[CH2:22][C:21](=[O:33])[NH:20][c:9]2[c:8]1[cH:13][c:12]([O:14][CH3:15])[c:11]([C:16]([F:17])([F:18])[F:19])[cH:10]2

Komponenten

Edukt 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 86586980{2-[3-(2-Cyano-pyridin-4-yl)-3-oxo-propionylamino]-5-methoxy-4-trifluoromethyl-phenyl}-carbamic acid tert.-butyl ester

Produkt 1

HCID 185488124-(8-Methoxy-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-pyridine-2-carbonitrile

Quellen und Nachweise

ORD-Eintrag: ord-1c284a0310e24cfebae627f690ea742d
Quelldatensatz: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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