6-Chloro-9H-beta-carbolin-8-amine → 5-(6-chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholine-4-carboxylic acid tert-butyl ester
Reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH:24]([C:31](=[O:32])[OH:33])[CH2:25][O:26][C:27]([CH3:29])([CH3:30])[CH2:28]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[cH:6][cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH2:15])[cH:14]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[cH:6][cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH:15][C:31]([CH:24]2[N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:28][C:27]([CH3:29])([CH3:30])[O:26][CH2:25]2)=[O:32])[cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-e70972493bd842bc80875cbba6f9c5fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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