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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1570962Generated: November 2, 2026

Ammonium → 3-Cyclobutyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethylphenyl)-amide

https://huagongshe.com/reaction/1570962

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantTetrahydrofuranHCID 8028—
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant3-Cyclobutyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl esterHCID 58218822—
ReactantButyllithiumHCID 178418339—
Product3-Cyclobutyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethylphenyl)-amideHCID 51034008—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-bdf459330527443193fb999091e48ccd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)