4-Fluorobenzyl bromide → 5-bromo-1'-[(5-chloro-2-thienyl)methyl]spiro[1-benzofuran-3,3'-indol]-2'(1'H)-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[C:7]1([CH2:8][O:9]2)[C:10](=[O:18])[NH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21.[Cl:41][c:42]1[s:43][c:44]([CH2:47][Cl:48])[cH:45][cH:46]1.[F:49][c:50]1[cH:51][cH:52][c:53]([CH2:54][Br:55])[cH:56][cH:57]1.[NH:20]1[c:21]2[c:22]([cH:23][cH:24][cH:25][cH:26]2)[C:27]2([c:28]3[cH:29][c:30]4[c:34]([cH:35][c:36]3[O:37][CH2:38]2)[O:33][CH2:32][O:31]4)[C:39]1=[O:40]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[C:7]1([CH2:8][O:9]2)[C:10](=[O:18])[N:11]([CH2:47][c:44]2[s:43][c:42]([Cl:41])[cH:46][cH:45]2)[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-daf8f1e2f80147c5b9d280ce91270866
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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