Pyridine → [8-chloro-2-(4-methoxyphenyl)-4-oxo-3,5-dihydro-2H-1,5-benzothiazepin-3-yl] acetate

HRID 1571456Notes

Reaction equation

HRID 1571456 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[S:10][c:11]3[c:12]([cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[NH:13][C:14](=[O:17])[CH:15]2[OH:16])[cH:7][cH:8]1.[CH3:23][C:24]([Cl:25])=[O:26].[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[S:10][c:11]3[c:12]([cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[NH:13][C:14](=[O:17])[CH:15]2[O:16][C:24]([CH3:23])=[O:26])[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 155934012-(4-methoxyphenyl)-3-hydroxy-8-chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one

Product 1

HCID 15593462[8-chloro-2-(4-methoxyphenyl)-4-oxo-3,5-dihydro-2H-1,5-benzothiazepin-3-yl] acetate

Sources & evidence

ORD record
ord-a9256f192e7440eea081f92c1d6c4597
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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