Dimethyl Sulfoxide → N-(1-benzylpiperidin-4-yl)-2-nitro-4-methylsulphonylaniline

HRID 1571485Notes

Reaction equation

HRID 1571485 reaction equation
[CH3:35][S:36]([CH3:37])=[O:38].[F:15][c:16]1[c:17]([N+:26](=[O:27])[O-:28])[cH:18][c:19]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:20][cH:21]1.[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1.[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34]>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1)[c:16]1[c:17]([N+:26](=[O:27])[O-:28])[cH:18][c:19]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:20][cH:21]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 923Sodium ion2×HCID 19660Carbonate IonHCID 3131371-Fluoro-4-methanesulfonyl-2-nitrobenzeneHCID 4158521-Benzyl-4-piperidylamine

Product 1

HCID 9281505N-(1-benzylpiperidin-4-yl)-2-nitro-4-methylsulphonylaniline

Sources & evidence

ORD record
ord-3bf3bea8975c418e924c6d931e8ad91d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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