1-(Bromomethyl)-4-(trifluoromethyl)benzene → ethyl 4-methyl-2-(5-oxo-1-((5-(trifluoromethyl)furan-2-yl)methyl)-1H-1,2,4-triazol-4(5H)-yl)thiazole-5-carboxylate
Reaction equation
[Br:13][CH2:14][c:15]1[o:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1.[CH3:24][c:25]1[n:26][c:27](-[n:35]2[cH:36][n:37][nH:38][c:39]2=[O:40])[s:28][c:29]1[C:30](=[O:31])[O:32][CH2:33][CH3:34].[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([c:15]1[o:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1)[n:38]1[n:37][cH:36][n:35](-[c:27]2[n:26][c:25]([CH3:24])[c:29]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[s:28]2)[c:39]1=[O:40]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5eef140c765b4e3f9ebcd62afcbb3853
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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