ethyl [3-(6-hydroxy-2,3-dihydro-1H-inden-5-yl)-3-(hydroxymethyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate → Ethyl(4'-bromo-5,6-difluoro-2'-oxospiro[1-benzofuran-3,3'-indol]-1'(2'h)-yl)acetate
Reaction equation
[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][C:12](=[O:13])[O:14][CH2:15][CH3:16])[C:5](=[O:17])[C:4]2([CH2:18][OH:19])[c:20]1[c:21]([OH:28])[cH:22][c:23]([F:27])[c:24]([F:26])[cH:25]1.[OH:29][c:30]1[cH:31][c:32]2[c:33]([cH:37][c:38]1[C:39]1([CH2:40][OH:41])[c:42]3[c:43]([cH:44][cH:45][cH:46][cH:47]3)[N:48]([CH2:49][C:50]([O:51][CH2:52][CH3:53])=[O:54])[C:55]1=[O:56])[CH2:34][CH2:35][CH2:36]2>>[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][C:12](=[O:13])[O:14][CH2:15][CH3:16])[C:5](=[O:17])[C:4]21[CH2:18][O:19][c:21]2[c:20]1[cH:25][c:24]([F:26])[c:23]([F:27])[cH:22]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d9d945549bd84c37b2c0f1029b14d165
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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