HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1572032Generated: October 31, 2026
Dimethylformamide → 1-(5-Tert-butylisoxazol-3-yl)-3-(3-(7-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propoxy)-6-methoxyquinazolin-4-yloxy)phenyl)urea
https://huagongshe.com/reaction/1572032
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| Reactant | Tetrabutylammonium | HCID 16028 | — |
| Reactant | Iodide Ion | HCID 30165 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-(5-Tert-butyl-isoxazol-3-yl)-3-{3-[7-(3-chloro-propoxy)-6-methoxy-quinazolin-4-yloxy]-phenyl}-urea | HCID 66876029 | — |
| Product | 1-(5-Tert-butylisoxazol-3-yl)-3-(3-(7-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propoxy)-6-methoxyquinazolin-4-yloxy)phenyl)urea | HCID 58267722 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
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| ORD ID | ord-9ec0a0c9f6f043ec8c748cf47f738099 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
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