1-(2-Hydroxyethyl)-4-methylpiperazine → 4-Chloro-6-methoxy-7-(2-(4-methylpiperazin-1-yl)ethoxy)quinazoline
Reaction equation
[CH3:15][N:16]1[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][OH:24])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:23][CH2:22][N:19]3[CH2:18][CH2:17][N:16]([CH3:15])[CH2:21][CH2:20]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-bca65aeca0f9450d9ee2afbb758540d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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