Acetonitrile → 4-[(3-Chloro-pyrazin-2-ylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([CH2:22][NH2:23])[CH2:20][CH2:21]1.[CH3:30][C:31]#[N:32].[Cl:1][c:2]1[n:3][cH:4][cH:5][n:6][c:7]1[Cl:8].[Cs+:28].[Cs+:29]>>[c:2]1([NH:23][CH2:22][CH:19]2[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:21][CH2:20]2)[n:3][cH:4][cH:5][n:6][c:7]1[Cl:8]Participants
6
Sources & evidence
- ORD record
- ord-a793e23e19744b2c91e70335354da13b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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