Potassium Cation → 2-(5-amino-pyridin-3-yl)-1-methyl-1H-indole

HRID 1572627Notes

Reaction equation

HRID 1572627 reaction equation
[BH:9]([OH:10])[OH:11].[CH3:12][n:13]1[cH:14][cH:15][c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]12.[CH3:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1.[K+:27].[K+:28].[K+:29].[NH2:1][c:2]1[cH:3][n:4][cH:5][c:6]([Br:8])[cH:7]1.[O:32]=[C:33]([CH:34]=[CH:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)[CH:42]=[CH:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[O:50]=[C:51]([CH:52]=[CH:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1)[CH:60]=[CH:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1.[O:68]=[C:69]([CH:70]=[CH:71][c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1)[CH:78]=[CH:79][c:80]1[cH:81][cH:82][cH:83][cH:84][cH:85]1.[P:22]([O-:23])([O-:24])([O-:25])=[O:26].[Pd:30].[Pd:31]>>[NH2:1][c:2]1[cH:3][n:4][cH:5][c:6](-[c:14]2[n:13]([CH3:12])[c:21]3[c:16]([cH:15]2)[cH:17][cH:18][cH:19][cH:20]3)[cH:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 1140TolueneHCID 117811-MethylindoleHCID 23938Palladium2×HCID 61668Boronic AcidHCID 95417Dibenzylidene acetone3×HCID 8176813-Amino-5-bromopyridine

Product 1

HCID 582155792-(5-amino-pyridin-3-yl)-1-methyl-1H-indole

Sources & evidence

ORD record
ord-4b23593391ab4eee9d73b29d65740384
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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