Methanol → 4-[2-(5-Chloro-2-fluorophenyl)-6,7-dihydrofuro[3,2-d]pyrimidin-4-ylamino]-nicotinic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][n:7][cH:8][cH:9][c:10]1[NH:11][c:12]1[c:13]2[c:14]([n:15][c:16](-[c:18]3[c:19]([F:25])[cH:20][cH:21][c:22]([Cl:24])[cH:23]3)[n:17]1)[CH2:26][CH2:27][O:28]2)=[O:29].[CH3:32][OH:33].[Na+:31].[OH-:30]>>[O:3]=[C:4]([c:5]1[cH:6][n:7][cH:8][cH:9][c:10]1[NH:11][c:12]1[c:13]2[c:14]([n:15][c:16](-[c:18]3[c:19]([F:25])[cH:20][cH:21][c:22]([Cl:24])[cH:23]3)[n:17]1)[CH2:26][CH2:27][O:28]2)[OH:29]Participants
5
Sources & evidence
- ORD record
- ord-492d3c8412f64f5d9773ad968f4ce5ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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