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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1572832Generated: October 25, 2026

2-Methyl-3-oxo-3-(phenylamino)propanoic acid → N1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-methyl-N3-phenylmalonamide

https://huagongshe.com/reaction/1572832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-3-oxo-3-(phenylamino)propanoic acidHCID 12605880—
ReactantN-(2-Methoxy-phenyl)-malonamic acidHCID 12664594—
ReactantN1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamideHCID 16040869—
Reactant3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamineHCID 59424480—
ProductN1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-methyl-N3-phenylmalonamideHCID 16041061—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-ccfe357558c24a9e987b91cd7b0caa3b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)