4-(4-Phenoxyphenyl)piperidine → 1-[3-(4-Fluorophenyl)prop-2-enyl]-4-(4-phenoxyphenyl)piperidine
Reaction equation
[F:20][c:21]1[cH:22][cH:23][c:24]([CH:25]=[CH:26][CH2:27][Br:28])[cH:29][cH:30]1.[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([CH:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[cH:12][cH:13]1>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([CH:14]2[CH2:15][CH2:16][N:17]([CH2:27][CH:26]=[CH:25][c:24]3[cH:23][cH:22][c:21]([F:20])[cH:30][cH:29]3)[CH2:18][CH2:19]2)[cH:12][cH:13]1Participants
3
Sources & evidence
- ORD record
- ord-a8874415f79840b3bd19ec30203b1064
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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