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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1573327Generated: October 25, 2026

Hydrochloric Acid → N-(4-(6-Cyano-7-((1-methylpiperidin-3-yl)methoxy)-4-quinolyl)oxy-2-fluorophenyl)-N'-(4-fluorophenyl)urea

https://huagongshe.com/reaction/1573327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant3-(Chloromethyl)-1-methylpiperidineHCID 103674—
ReactantSodiumHCID 5360545—
Reactant1-[4-(6-Cyano-7-hydroxyquinolin-4-yl)oxy-2-fluorophenyl]-3-(4-fluorophenyl)ureaHCID 135829378—
ProductN-(4-(6-Cyano-7-((1-methylpiperidin-3-yl)methoxy)-4-quinolyl)oxy-2-fluorophenyl)-N'-(4-fluorophenyl)ureaHCID 22936564—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-17e8ab8543f143c29cc3e211b8772dec
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)