Carbonate Ion → N-(4-(7-(3-(7-hydroxy-5-azaspiro[2.4]heptane-5-yl)propoxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Reaction equation
[C:54](=[O:55])([O-:56])[O-:57].[CH3:38][S:39]([O:40][CH2:43][CH2:44][CH2:45][N:46]1[CH2:47][C:48]2([CH2:49][CH2:50]2)[CH:51]([OH:53])[CH2:52]1)(=[O:41])=[O:42].[Cs+:58].[Cs+:59].[F:1][c:2]1[cH:3][c:4]([N:22]([C:23](=[O:24])[C:25]2([C:28](=[O:29])[NH2:30])[CH2:26][CH2:27]2)[c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][n:12][c:13]2[cH:14][c:15]([OH:21])[c:16]([O:19][CH3:20])[cH:17][c:18]12>>[F:1][c:2]1[cH:3][c:4]([N:22]([C:23](=[O:24])[C:25]2([C:28](=[O:29])[NH2:30])[CH2:26][CH2:27]2)[c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][n:12][c:13]2[cH:14][c:15]([O:21][CH2:43][CH2:44][CH2:45][N:46]3[CH2:47][C:48]4([CH2:49][CH2:50]4)[CH:51]([OH:53])[CH2:52]3)[c:16]([O:19][CH3:20])[cH:17][c:18]12Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c455acd0700f499c87e5538c6a4afbe6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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