4-Fluorobenzyl bromide → Ethyl 2-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

HRID 1573450Notes

Reaction equation

HRID 1573450 reaction equation
[Br:1][CH2:2][CH:3]1[CH2:4][C:5]1([F:6])[F:7].[CH3:17][c:18]1[n:19][c:20]([N:28]2[C:29](=[O:33])[NH:30][CH2:31][CH2:32]2)[s:21][c:22]1[C:23](=[O:24])[O:25][CH2:26][CH3:27].[F:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][Br:14])[cH:15][cH:16]1>>[F:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][N:30]2[C:29](=[O:33])[N:28]([c:20]3[n:19][c:18]([CH3:17])[c:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[s:21]3)[CH2:32][CH2:31]2)[cH:15][cH:16]1

Participants

4

Reactant 3

HCID 680214-Fluorobenzyl bromideHCID 27614022-(Bromomethyl)-1,1-difluorocyclopropaneHCID 57919776Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate

Product 1

HCID 57919911Ethyl 2-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

Sources & evidence

ORD record
ord-2f7a77afa1ec46dd8fbee3ba85753b9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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