Dimethyl Sulfoxide → N-cyclopropyl-2-methyl-3-(4-ethoxycarbonyl-1-piperazinyl)-4-fluoro-6-nitroaniline
Reaction equation
[CH3:24][S:25]([CH3:26])=[O:27].[CH:30]1([NH2:33])[CH2:31][CH2:32]1.[F-:28].[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[CH2:17][CH2:18]2)[c:4]([CH3:12])[c:5]([F:11])[c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[K+:29].[OH2:34]>>[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[CH2:17][CH2:18]2)[c:4]([CH3:12])[c:5]([NH:33][CH:30]2[CH2:31][CH2:32]2)[c:6]([N+:8](=[O:9])[O-:10])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-2d0e6968dac3483f8d9d45cb86479260
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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