4-(2-Amino-1-hydroxyethyl)benzene-1,3-diol → N-(4-{[4-(4-{[2-(2,4-Dihydroxyphenyl)-2-hydroxyethyl]amino}-1-piperidineyl)-anilino]sulfonyl}phenyl)acetamide

HRID 157357Notes

Reaction equation

HRID 157357 reaction equation
[NH2:28][CH2:29][CH:30]([OH:31])[c:32]1[c:33]([OH:39])[cH:34][c:35]([OH:38])[cH:36][cH:37]1.[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11]([NH:14][S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][c:21]([NH:24][C:25]([CH3:26])=[O:27])[cH:22][cH:23]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1>>[CH:2]1([NH:28][CH2:29][CH:30]([OH:31])[c:32]2[c:33]([OH:39])[cH:34][c:35]([OH:38])[cH:36][cH:37]2)[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11]([NH:14][S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][c:21]([NH:24][C:25]([CH3:26])=[O:27])[cH:22][cH:23]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 167683114-(2-Amino-1-hydroxyethyl)benzene-1,3-diolHCID 22220411N-{4-[4-(4-Oxo-piperidin-1-yl)-phenylsulfamoyl]-phenyl}-acetamide

Product 1

HCID 22220536N-(4-{[4-(4-{[2-(2,4-Dihydroxyphenyl)-2-hydroxyethyl]amino}-1-piperidineyl)-anilino]sulfonyl}phenyl)acetamide

Sources & evidence

ORD record
ord-c4c0393b6b2f42e6ad227d469583db37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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