N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline-1-carboxamide → 5-(3-amino-6-(4-(N-cyclopropyl-N-methylsulfamoyl)phenyl)pyrazin-2-yl)-N-methylindoline-1-carboxamide
Reaction equation
[CH3:1][NH:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[cH:9][c:10]([B:14]3[O:15][C:16]([CH3:17])([CH3:18])[C:19]([CH3:20])([CH3:21])[O:22]3)[cH:11][cH:12][c:13]21.[NH2:23][c:24]1[n:25][cH:26][c:27](-[c:31]2[cH:32][cH:33][c:34]([S:37](=[O:38])(=[O:39])[N:40]([CH3:41])[CH:42]3[CH2:43][CH2:44]3)[cH:35][cH:36]2)[n:28][c:29]1[Br:30]>>[CH3:1][NH:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[cH:9][c:10](-[c:29]3[c:24]([NH2:23])[n:25][cH:26][c:27](-[c:31]4[cH:32][cH:33][c:34]([S:37](=[O:38])(=[O:39])[N:40]([CH3:41])[CH:42]5[CH2:43][CH2:44]5)[cH:35][cH:36]4)[n:28]3)[cH:11][cH:12][c:13]21Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-850361b1fe3144b8a7f4bd5110201b9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…