HRID1573914

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6342

Acetonitrile

C2H3N

HCID12679

Hexamethylphosphoramide

C6H18N3OP

HCID24386

Thionyl Chloride

Cl2OS

HCID75809

4-Bromobutyric acid

C4H7BrO2

HCID69308994

4-Amino-N-(2-benzoylphenyl)benzene-1-sulfonamide

C19H16N2O3S

PRODUCTS

产物

HCID58664932

N-(2-Benzoylphenyl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

C23H20N2O4S

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-bc4dd1945c0641b48fd1287c871de1b9
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应SMILES

[Br:1][CH2:2][CH2:3][CH2:4][C:5](=[O:6])[OH:7].[CH3:37][N:38]([CH3:39])[P:40]([N:41]([CH3:42])[CH3:43])([N:44]([CH3:45])[CH3:46])=[O:47].[CH3:48][C:49]#[N:50].[NH2:12][c:13]1[cH:14][cH:15][c:16]([S:19](=[O:20])(=[O:21])[NH:22][c:23]2[c:24]([C:29]([c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)=[O:36])[cH:25][cH:26][cH:27][cH:28]2)[cH:17][cH:18]1.[S:8]([Cl:9])([Cl:10])=[O:11]>>[CH2:2]1[CH2:3][CH2:4][C:5](=[O:7])[N:12]1[c:13]1[cH:14][cH:15][c:16]([S:19](=[O:20])(=[O:21])[NH:22][c:23]2[c:24]([C:29]([c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)=[O:36])[cH:25][cH:26][cH:27][cH:28]2)[cH:17][cH:18]1