HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15741Generated: October 27, 2026
Dimethylformamide dimethyl acetal → Ethyl 1-(4-chlorophenylsulfonyl)-3-((dimethylamino)methylene)-4-oxo-1,2,3,4-tetrahydropyridine-2-carboxylate
https://huagongshe.com/reaction/15741
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Ethyl 1-(4-chlorophenylsulfonyl)-4-oxo-1,2,3,4-tetrahydropyridine-2-carboxylate | HCID 59342383 | — |
| Product | Ethyl 1-(4-chlorophenylsulfonyl)-3-((dimethylamino)methylene)-4-oxo-1,2,3,4-tetrahydropyridine-2-carboxylate | HCID 68502343 | — |
Reaction Steps
Compound 103 (5.0 g, 15 mmol) was dissolved in DMF-DMA (20 mL) and heated at 100° C. for 30 minutes. The reaction mixture was concentrated in vacuo to yield compound 104 as a yellow oil that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07732609B2 |
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| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-916c1a439c9a48dfb8e5e3b3454c7fcd |
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| Source note | uspto-grants-2010_06 |
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