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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1574428Generated: October 29, 2026

Water → 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-(5-(5-(4-isopropylpiperazin-1-yl)pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)benzyl acetate

https://huagongshe.com/reaction/1574428

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPalladiumHCID 23938—
Reactant1,4-DioxaneHCID 31275—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetateHCID 59473769—
Reactant6-chloro-4-(5-(4-isopropylpiperazin-1-yl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-oneHCID 66742221—
Product2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-(5-(5-(4-isopropylpiperazin-1-yl)pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)benzyl acetateHCID 66743191—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-8bfab6c4f1aa4173a0d285c50dfe1512
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)