Methyl 4-methoxyacetoacetate → 2-[4-({[4-Methoxymethyl-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carbonyl]-amino}-methyl)-phenoxy]-2-methyl-propionic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH2:16])[cH:13][cH:14]1)=[O:17].[CH3:18][O:19][CH2:20][c:21]1[n:22][c:23](-[c:30]2[cH:31][cH:32][c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]2)[n:24][cH:25][c:26]1[C:27](=[O:28])[OH:29].[CH3:40][O:41][C:42](=[O:43])[CH2:44][C:45](=[O:46])[CH2:47][O:48][CH3:49]>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH:16][C:27]([c:26]2[c:21]([CH2:20][O:19][CH3:18])[n:22][c:23](-[c:30]3[cH:31][cH:32][c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]3)[n:24][cH:25]2)=[O:28])[cH:13][cH:14]1)=[O:17]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-56b65b1430b44a3699d49dc4c4bb6304
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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