Dichloromethane → N-[4-chloro-3-(trifluoromethyl)phenyl]-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxamide

HRID 1574487Notes

Reaction equation

HRID 1574487 reaction equation
[B:27]([Br:28])([Br:29])[Br:30].[Cl:1][c:2]1[c:3]([C:23]([F:24])([F:25])[F:26])[cH:4][c:5]([NH:8][C:9](=[O:10])[CH:11]2[CH2:12][c:13]3[cH:14][c:15]([O:21][CH3:22])[cH:16][cH:17][c:18]3[CH2:19][CH2:20]2)[cH:6][cH:7]1.[Cl:31][CH2:32][Cl:33]>>[Cl:1][c:2]1[c:3]([C:23]([F:24])([F:25])[F:26])[cH:4][c:5]([NH:8][C:9](=[O:10])[CH:11]2[CH2:12][c:13]3[cH:14][c:15]([OH:21])[cH:16][cH:17][c:18]3[CH2:19][CH2:20]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 58902339N-[4-chloro-3-(trifluoromethyl)phenyl]-7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxamide

Product 1

HCID 58902317N-[4-chloro-3-(trifluoromethyl)phenyl]-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxamide

Sources & evidence

ORD record
ord-cda90882ce384b09bbdf68c713a80eaa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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