4-Amino-2,5-dimethylphenol → N2-(2,5-dimethyl-4-hydroxyphenyl)-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

HRID 1574594Notes

Reaction equation

HRID 1574594 reaction equation
[CH3:20][c:21]1[c:22]([NH2:23])[cH:24][c:25]([CH3:29])[c:26]([OH:28])[cH:27]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1>>[c:2]1([NH:23][c:22]2[c:21]([CH3:20])[cH:27][c:26]([OH:28])[c:25]([CH3:29])[cH:24]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1

Participants

3

Reactant 2

HCID 765444-Amino-2,5-dimethylphenolHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

Product 1

HCID 22060954N2-(2,5-dimethyl-4-hydroxyphenyl)-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-62b191d90a7c4a929b4b2aa52bb151c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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