1-(3,5-Difluorophenyl)piperazine → 1-[(5-Acetyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3,5-difluorophenyl)piperazine
Reaction equation
[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([NH:13][C:14]([O:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)=[O:22])[c:7]([O:11][CH3:12])[n:8][c:9]1[CH3:10].[F:23][c:24]1[cH:25][c:26]([N:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[cH:27][c:28]([F:30])[cH:29]1>>[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([NH:13][C:14](=[O:22])[N:34]2[CH2:33][CH2:32][N:31]([c:26]3[cH:25][c:24]([F:23])[cH:29][c:28]([F:30])[cH:27]3)[CH2:36][CH2:35]2)[c:7]([O:11][CH3:12])[n:8][c:9]1[CH3:10]Participants
3
Sources & evidence
- ORD record
- ord-900fb35a89e54249916a230a3839705c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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